Motherly Roles free essay sample

Motherly Roles In the spirit of Mother’s Day approaching, I felt it only obligatory to talk about the mothers in the novels in which I’ve read. I could mention the first lady in which I read in class from the novel â€Å"The Great Gatsby†, although this lady being Daisy Buchanan wasn’t much of a motherly role to commend. The mother I’d like to take my hat off to would be Ma Joad in â€Å"The Grapes of Wrath. † In comparison to a great motherly role is Mrs. Kelly in â€Å"The Heart is a Lonely Hunter. † These are two mothers who would do anything to keep their families together. What is a mother? Yes, a mother is one who has conceived, given birth, and raised children through their own social, cultural, and religious differences. A mother is gentle, yet strong. A mother always shows you just how much she cares and always makes you feel as if you belong, even though you may feel she is completely off. We will write a custom essay sample on Motherly Roles or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page A mother is a dependable source of comfort, a cushion when you fall, a constant supporter through indecisive decisions, and one who gives guidance while you’ve drifted through a dark tunnel. No wonder we pay much tribute to our mothers. They are with us through think and thin and through the good times and the bad. From the six novels discussed in class, I believe Ma Joad from â€Å"The Grapes of Wrath† amplifies the mother role. John Steinbeck writes an endearing novel, â€Å"The Grapes of Wrath† about love, lose, hopes, struggle and the importance of family. Ma Joad was the courage, wisdom, and matriarch of the family. She was the mother to the main character/narrator Tom Joad. Whenever the Joads were ready to give up, Ma Joad would reinforce them with enough courage to go on. She even gave the voice of reason to Pa Joad when he was too weak and losing his place as head of the household, the voice of reason to keep him from giving up. She was the strongest person in the whole family. She not only had to be the right hand for her husband, but the strongest person for the whole family. She always had reassuring words to keep her family moving such as, â€Å"us people will go on living when all them people is gone. † When someone needed reassurance or advice, she was there for those who needed some guidance. Ma Joad was a woman of experience, which made her so wise to those she ncountered. She was the matriarch of her family as the head woman of her household. She is always strong and helpful, wise and courageous. She has the same fears as the rest of her family, but she keeps it well hidden to show her triumph through such hard times. Later in the book, Pa Joad actually looses his place as head of the household in weakness and Ma took charge. Itâ€⠄¢s hard to compare another mother to Mrs. Joad from the selected novels, but at least one did spark my interest. â€Å"The Heart is a Lonely Hunter† was Carson McCullers first novel published in 1940 when she was only twenty-three years old. She wrote her novel as an autobiography, which is ironic because it is her mother that truly stands out now and not the fictional character I thought she was. But for the sake of making things simple, I’ll just stick with the character in the novel. Carson McCullers herself was raised in Columbus, Georgia. Her father was a watchmaker, like in the novel, who also owned his own jewelry shop. In her early teen years her parents supported her in her interest in music. This support structure and the few glimpses of Mrs. Kelly is where I drew the conclusion that she is a good mother and deserves to be compared to Ma Joad. Although, the comparison will be short and far between, she is a mother none-the-less and more so than Daisy Buchanan in â€Å"The Great Gatsby,† for example. Mrs. Kelly in the novel â€Å"The Heart is a Lonely Hunter† is a mother to six children. Imagining six children in present time 2000 is difficult to even fathom with the economy dropping, but six children in the 1940’s just directly after the Great Depression, it seems impossible. Mrs. Kelly’s husband breaks his hip at his carpenter hob and is restricted to a wheel chair until he recuperates. His unfortunate outcome has him running a watch-repair business out of his own home. While, Mrs. Kelly helps with the watch-repair and takes care of the children as well as runs a dry cleaning out of their home. She offers to take in boarders to help put food on the table. With a husband unable to do fatherly roles, she hires a maid named Portia to help raise the younger children, cook, and clean. The family is considered poor in statue, but it doesn’t deteriorate from wanting the best for her family. Now in a time rebuilding from the Great Depression, most families are living the same, unless living a background of wealthy grandparents and great grandparents. She is an ideal mother of today and of definition. What makes a good mother? This is a pertinent question and one, which should never just be answered in a few words. Mothers are comprised with a bundle of emotions that defy reason. Mothers are meant to be there spiritually, physically, emotionally, and in modern society, financially as well. Ma Joad and Mrs. Kelly cannot be compared completely to one another since they do have different backgrounds and different situations at their foot beds. As per contrasting them, there is none, and there is no doubt in my mind that they are mothers one in the same.

Free Essays on The Dayton Paris Peace Agreement on Bosnia

CURRENT DEVELOPMENTS THE PROTECTION OF HUMAN RIGHTS THROUGH THE DAYTON/PARIS PEACE AGREEMENT ON BOSNIA The Bosnia Proximity Peace Talks at the Wright-Patterson Air Force Base near Dayton, Ohio, took place from November 1 to 21, 1995, and ended with the initialing of the General Framework Agreement for Peace in Bosnia and Herzegovina (GFA) 1 and several of the annexed or related instruments by representatives of the principal states parties to the conflict in Bosnia: the Republic of Bosnia and Herzegovina, the Republic of Croatia and the Federal Republic of Yugoslavia. The initialing was witnessed by representatives of the European Union and the five states members of the Contact Group on Bosnia. In addition, all of the twelve instruments annexed to the GFA were also initialed or otherwise endorsed on behalf of the Federation of Bosnia and Herzegovina and the Republika Srpska. The GFA and these instruments were formally signed in Paris on December 14, and thereby immediately entered i nto force. 2 As the violation of human rights was one of the central aspects of nearly four years of conflict in Bosnia, it was always understood that measures for protecting those rights would have to be one of the principal features of any settlement. The present Note describes the extensive, innovative and somewhat intricate human rights provisions of the Dayton/ Paris Peace Agreement, tracing many of them to certain earlier proposals that had been made in various international fora. 3 Now these provisions are embedded in the complex web of instruments formulated in Dayton, whose interactions must also be considered. SEQUENCE OF CONSTITUTIONAL PROPOSALS Long before negotiations opened at the Wright-Patterson Air Force Base, the constitutional rearrangement of, first, the former Socialist Federal Republic of Yugoslavia (SFRY) and, then, of the emerging Republic of Bosnia and Herzegovina became the subject of international negotiations, in all of which the ... Free Essays on The Dayton Paris Peace Agreement on Bosnia Free Essays on The Dayton Paris Peace Agreement on Bosnia CURRENT DEVELOPMENTS THE PROTECTION OF HUMAN RIGHTS THROUGH THE DAYTON/PARIS PEACE AGREEMENT ON BOSNIA The Bosnia Proximity Peace Talks at the Wright-Patterson Air Force Base near Dayton, Ohio, took place from November 1 to 21, 1995, and ended with the initialing of the General Framework Agreement for Peace in Bosnia and Herzegovina (GFA) 1 and several of the annexed or related instruments by representatives of the principal states parties to the conflict in Bosnia: the Republic of Bosnia and Herzegovina, the Republic of Croatia and the Federal Republic of Yugoslavia. The initialing was witnessed by representatives of the European Union and the five states members of the Contact Group on Bosnia. In addition, all of the twelve instruments annexed to the GFA were also initialed or otherwise endorsed on behalf of the Federation of Bosnia and Herzegovina and the Republika Srpska. The GFA and these instruments were formally signed in Paris on December 14, and thereby immediately entered i nto force. 2 As the violation of human rights was one of the central aspects of nearly four years of conflict in Bosnia, it was always understood that measures for protecting those rights would have to be one of the principal features of any settlement. The present Note describes the extensive, innovative and somewhat intricate human rights provisions of the Dayton/ Paris Peace Agreement, tracing many of them to certain earlier proposals that had been made in various international fora. 3 Now these provisions are embedded in the complex web of instruments formulated in Dayton, whose interactions must also be considered. SEQUENCE OF CONSTITUTIONAL PROPOSALS Long before negotiations opened at the Wright-Patterson Air Force Base, the constitutional rearrangement of, first, the former Socialist Federal Republic of Yugoslavia (SFRY) and, then, of the emerging Republic of Bosnia and Herzegovina became the subject of international negotiations, in all of which the ...

Civil War Admiral David G. Farragut

Civil War Admiral David G. Farragut David Farragut - Birth Early Life: Born July 5, 1801, in Knoxville, TN, David Glasgow Farragut was the son of Jorge and Elizabeth Farragut. Jorge, a Minorcan immigrant during the American Revolution, was a merchant captain as well as a cavalry officer in the Tennessee militia. Naming his son James at birth, Jorge soon moved the family to New Orleans. While residing there, he aided the father of future Commodore David Porter. Following the elder Porters death, the commodore offered to adopt young James and train him as a naval officer in gratitude for the services rendered to his father. In recognition of this, James changed his name to David. David Farragut - Early Career War of 1812: By joining the Porter family, Farragut became foster brothers with the other future leader of the Union Navy, David Dixon Porter. Receiving his midshipmans warrant in 1810, he attended school, and later sailed aboard USS Essex with his adopted father during the War of 1812. Cruising in the Pacific, Essex captured several British whalers. Midshipman Farragut was given command of one of the prizes and sailed it to port before rejoining Essex. On March 28, 1814, Essex lost its main topmast while leaving Valparaiso and was captured by HMS Phoebe and Cherub. Farragut fought bravely and was wounded in the battle. David Farragut - Post-War Personal Life: Following the war, Farragut attended school and made two cruises to the Mediterranean. In 1820, he returned to home and passed his lieutenants exam. Moving to Norfolk, he fell in love with Susan Marchant and married her in 1824. The two were married for sixteen years when she died in 1840. Moving through a variety of posts, he was promoted to commander in 1841. Two years later, he married Virginia Loyal of Norfolk, with whom he would have a son, Loyall Farragut, in 1844. With the outbreak of the Mexican-American War in 1846, he was given command of USS Saratoga, but saw no major action during the conflict. David Farragut - War Looms: In 1854, Farragut was at dispatched to California to establish a naval yard at Mare Island near San Francisco. Working for four years, he developed the yard into the US Navys premier base on the west coast and was promoted to captain. As the decade drew to a close, the clouds of civil war began to gather. A Southerner by birth and residence, Farragut decided that if a peaceful separation of the country were to occur, that he would consider remaining in the South. Knowing that such a thing would not be permitted to happen, he declared his allegiance to the national government and moved his family to New York. David Farragut - Capture of New Orleans: On April 19, 1861, President Abraham Lincoln declared a blockade of the Southern coast. To enforce this edict, Farragut was promoted to Flag Officer and sent aboard USS Hartford to command the West Gulf Blockading Squadron in early 1862. Charged with eliminating Confederate commerce, Farragut also received orders to operate against the Souths largest city, New Orleans. Assembling his fleet and a flotilla of mortar boats at the mouth of the Mississippi, Farragut began scouting the approaches the city. The most formidable obstacles were Forts Jackson and St. Philip as well as a flotilla of Confederate gunboats. After approaching the forts, Farragut ordered the mortar boats, commanded by his step brother David D. Porter, to open fire on April 18. After six days of bombardment, and a daring expedition to cut a chain stretched across the river, Farragut ordered the fleet to move forward. Steaming at full speed, the squadron raced passed the forts, guns blazing, and safely reached the waters beyond. With Union ships in their rear, the forts capitulated. On April 25, Farragut anchored off New Orleans and accepted the citys surrender. Shortly thereafter, infantry under Maj. Gen. Benjamin Butler arrived to occupy the city. David Farragut - River Operations: Promoted to rear admiral, the first in US history, for his capture of New Orleans, Farragut began pressing up the Mississippi with his fleet, capturing Baton Rouge and Natchez. In June, he ran the Confederate batteries at Vicksburg and linked up with the Western Flotilla, but was unable to take the city due to a lack of troops. Returning to New Orleans, he received orders to steam back to Vicksburg to support Maj. Gen. Ulysses S. Grants efforts to capture the city. On March 14, 1863, Farragut attempted to run his ships by the new batteries at Port Hudson, LA, with only Hartford and USS Albatross succeeding. David Farragut - Fall of Vicksburg and Planning for Mobile: With only two ships, Farragut began patrolling the Mississippi between Port Hudson and Vicksburg, preventing valuable supplies from reaching Confederate forces. On July 4, 1863, Grant successfully concluded his siege of Vicksburg, while Port Hudson fell on July 9. With the Mississippi firmly in Union hands, Farragut turned his attention to the Confederate port of Mobile, AL. One of the largest remaining ports and industrial centers in the Confederacy, Mobile was defended by Forts Morgan and Gaines at the mouth of Mobile Bay, as well as by Confederate warships and large torpedo (mine) field. David Farragut - Battle of Mobile Bay: Assembling fourteen warships and four ironclad monitors off Mobile Bay, Farragut planned to attack on August 5, 1864. Inside the bay, Confederate Adm. Franklin Buchanan had the ironclad CSS Tennessee and three gunboats. Moving toward the forts, the Union fleet suffered the first loss when the monitor USS Tecumseh struck a mine and sank. Seeing the ship go down, USS Brooklyn paused, sending the Union line into confusion. Lashing himself to Hartfords rigging to see over the smoke, Farragut exclaimed Damn the torpedoes! Full speed ahead! and led his ship into the bay with the rest of fleet following. Charging through the torpedo field without any losses, the Union fleet poured into the bay to do battle with Buchanans ships. Driving away the Confederate gunboats, Farraguts ships closed on CSS Tennessee and battered the rebel vessel into submission. With Union ships in the bay, the forts surrendered and military operations against the city of Mobile began. David Farragut - End of the War and Aftermath In December, with his health failing, the Navy Department ordered Farragut home for a rest. Arriving in New York, he was received as a national hero. On December 21, 1864, Lincoln promoted Farragut to vice admiral. The next April, Farragut returned to duty serving along the James River. Following the fall of Richmond, Farragut entered the city, along with Maj. Gen. George H. Gordon, just prior to President Lincolns arrival. After the war, Congress created the rank of admiral and immediately promoted Farragut to the new grade in 1866. Dispatched across the Atlantic in 1867, he visited the capitals of Europe where he was received with the highest honors. Returning home, he remained in the service despite declining health. On August 14, 1870, while vacationing at Portsmouth, NH, Farragut died of a stroke at the age of 69. Buried at Woodlawn Cemetery in New York, over 10,000 sailors and soldiers marched in his funeral procession, including President Ulysses S. Grant.

MPM IP3 Essay Example | Topics and Well Written Essays - 750 words

MPM IP3 - Essay Example This paper tries to explain the roles and importance of WBS to any project tasks in the organization as well as identifying the purpose of the roles, the responsibilities of the roles, the reporting relationship of the roles, skills, qualifications, and experiences required (Haugan, 2002). Project teams are groups of people who are responsible for a proper planning and execution of the project. Project teams consist of the project manager, and a number of members of the project team, they are brought to deliver the tasks assigned for them in considerate to the scheduled project. The project manager is one who is responsible in making sure that the projects or tasks allocated are completed by the project team. He develops a project plan with teams and manages team’s performance of the project tasks. The key responsibility of a project manager is to secure an acceptance plus the approvals of the deliverables from the project sponsor as well as stakeholders. The project manager is also responsible for status reporting, for communication and risk management, and makes sure that projects are delivered at the correct time. There are some larger projects, which require project team members who may act as Team leads. Team leads provides tasks, and other technical leadership they sometimes maintains apportion of a project plan. The other project team member is the executive sponsor who is a manager and demonstrates the interest in out coming of the project; he is also responsible for securing as well as resources for project. Actually, an executive sponsor is the highest-ranking manager in project plan. The executive sponsor has the responsibility of providing support to the project, and has gotten the final approval of the scope changes as well as, signing off the approvals of succeeding the project phase. He may also elect delegates, which are above the responsibility to project Director. Other project

Case study on Western States University Hospital Essay

Case study on Western States University Hospital - Essay Example In the present case, the lack of nursing leadership is the main reason that information system is not being used to its full potential. The importance of IT/IS system needs to disseminated amongst the employees so that they are able to understand the vast potential of computer and how it would improve and improvise their performance outcome. The success of system could only realized when the people who are directly involved with the various aspects of the information, ensure that small effort from them would significantly impact the outcome of the necessary outcome. ABC system is fully capable of coordinating activities and ensuring smooth operation of the hospital when details of patients are entered timely. While admitting clerks need to fill in the initial details of the patients, the discharge and transfer of patients need to be timely entered within the database by the nursing staff to produce updated reports of the patients. There is definitely huge room for improvement. The basic purpose of all business is to strive for improved performance. The hospital management must also ensure performance improvement through leadership initiatives that promote team building, shared goals and collective decision making. Indeed, performance measurement and improvement have increasingly become key issues in healthcare delivery. Meeting the needs and requirements of patients are the major objectives of effective healthcare delivery system.... Hence, in the present case, development of core performance improvement team would help to motivate, inform and train the employees, especially nursing staff, in improving their individual and collective performance for improved results. The most appropriate type of PI team would be the one that understands that knowledge leads to empowerment so that people can make decisions based on informed choices. Hence, team members must comprise of persons who have strong cross cultural understanding and understand the implicit and explicit importance of technology. The main goal of the team would be to identify the areas where the creative inputs of the staff would impact on the performance. The necessary linkages like training of staff on new skills would also be part of PI team so that staff can keep up with the on-going changes within and outside the organizations and ensure continuous improvement in their performance. Answer 3 Organizational structure of hospital is complex in its deliver y of goals. Smooth operations within its various departments become critical part of its success. The PI team of the hospitals should therefore, comprise of managers and leaders from different department. Nurses, physicians, administrators, clinicians, dieticians and pharmacists should be included. They should understand the need for continuous improvement of performance and have clearly defined goals for their team and provided with requisite knowledge skills to achieve their target. The team members must be educated on the need for coordinated efforts to achieve the wider goals and objectives of the hospitals. Nurses and physicians are intrinsic part of healthcare industry that is directly

The plague Essay Essay Example for Free

The plague Essay Essay The plague that wiped out one-third of the population of Western Europe in the 14th century was nondiscriminatory. Many reasons contributed to the large number of deaths. The plague was a turning point in Europe socially, economically and culturally. There were several ways in which the plague affected Europe. One of the reasons the plague affected Europe was socially. This was the by-product of a single flea bite. Erasmus of Rotterdam states, â€Å"The plague and sickness in England is due to the filth in the streets and the sputum and dogs’ urine†¦Ã¢â‚¬  which could be close to the correct answer because the fleas infected the rats and then the rats infected other animals which then infected the humans. Giovan Flippo a physician seemed to think people in higher positions would try to take power from some and frighten others. With so many deaths, Europe was socially devastated. Economy was another reason why the plague affected the people of Europe. â€Å"Since the rich fled, death was principally directed towards the poor†¦Ã¢â‚¬  explains French author Nicolas Versoris. This means the poor were left to die and infect more of the poor people while the rich were able to flee. According to M. Bertrand, physician at Marseilles argues â€Å"The plague must be considered a particular chastisement exercised by an angry god†¦Ã¢â‚¬ . Meaning that it was god’s way of showing his anger by taking the lives of people. Again, the plague took the lives from all walks of life, whether rich or poor. So many people died that there weren’t enough people to do jobs therefore a labor shortage occurred. Finally culture played another significant role. Cultural beliefs play an important part in the decision making process for people. â€Å"†¦sent me a little piece of bread that had touched the body of St. Domenica. I fed it to my husband and suddenly the fever broke†, mentioned Lisabetta Centenni, Italian housewife. She believed that her husband was cured by the holy piece of bread because it touched the body of St. Domenica. A French physician, H. de Rochas seemed to think that wearing toads around the necks of the infected would draw the venom of the plague out of their bodies.

America’s Great War: World War I and the American Experience by Robert

America’s Great War: World War I and the American Experience by Robert H. Zieger In the book, America’s Great War: World War I and the American Experience, Robert H. Zieger discusses the events between 1914 through 1920 forever defined the United States in the Twentieth Century. When conflict broke out in Europe in 1914, the President, Woodrow Wilson, along with the American people wished to remain neutral. In the beginning of the Twentieth Century United States politics was still based on the â€Å"isolationism† ideals of the previous century. The United States did not wish to be involved in European politics or world matters. The U.S. goal was to expand trade and commerce throughout the world and protect the borders of North America. The American belief at the beginning of the war was that it would be short conflict reminiscent of the fight between Germany and France in 1870(Zieger, 9). At the time both the Allies and the Central Powers, along with Americans, miscalculated the impact the involvement of American forces could have for either side. The U.S. Navy was expanded and upgraded during the presidency of Theodore Roosevelt but the Army was still a minimal force. To keep with the â€Å"true neutrality† the United States initially refused to aid either side with supplies or economic assistance. Once the battles became entrenched and a â€Å"war of attrition† began, the European nations continued to look toward the United States for aid. As American financial institutions and exporters sought guidance from Wilson’s administration they received a different answer: â€Å"short term loans and credits by American financial institutions to belligerents in connection with trade were acceptable† (Zieger, 11). Americans could not over look the potential economic boost that could be achieved by supplying the European nations with food, supplies and weapons orders being requested. Both sides accepted the United States’ aid but they also sought to cut-off each other’s supply chain. While the Allies barricaded Germany’s ports with the British Navy, Germany began attacking merchant ships using their submarines, or U-boats. While Wilson was angered by the British tactics he was even more infuriated by the German’s. This would be the ultimate end of U.S. neutrality as Wilson would sternly address Germany’s actions and not Britain’s. In 1915 a German U-boat sank a Brit... ... to be President afterwards. His unwillingness to compromise with the Senate caused the Treaty of Versailles along with the League of Nations never to be ratified by the United States. The notion of the League of Nations that won Wilson a Noble Peace Prize in 1920 was never joined his own country. After the election of 1920 America would return to its isolationism roots and watch as the nations of Europe headed down a path for another world war. As Americans watched Communism rise in Russia they questioned for the first time the patronage of their fellow Americans. Economic and social reforms that started up during the war were set to a status-quo mentality. The actions set forward from the Treaty of Versailles and stance the U.S. Congress took on the League of Nations would eventually lead the world in the worst depression ever and ultimately to a second world war in a mere twenty years. Works Cited: Zieger, Robert H. (2000). America’s Great War: World War I and the American Experience. Lanham, MD: Rowman & Littlefield Publishers Inc. Davidson, J. (Ed.). (2002). Nation of nations: A concise narrative of the American republic. (3rd ed., Vol. 2). New York: McGraw-Hill

Anemia Essay

1. Differentiate between absolute and functional iron deficiency in the context of ACD and IDA. Absolute iron deficiency is when the stores of iron are depleted and bone marrow iron is absent, resulting in low serum ferritin and low transferrin saturation. Simple absolute iron deficiency usually results in iron deficiency anemia and can be resolved with iron supplementation. Functional iron deficiency results in anemia of chronic disease/inflammation, where infections, connective tissue disorders, or other diseases can cause inflammatory cytokines to be released. These inflammatory cytokines inhibit survival of erythroid progenitor cells, reduce EPO production, and cause excess hepcidin production, which decreases the amount of iron absorbed by enterocytes and blocks the release of iron stored in macrophages. In this case, the iron stores in the body are adequate, but are not being released for use, resulting in hypoferremia and creating a pathological basis for ACD. 2. Explain why transferrin levels in the blood are not increased in ACD patients, unlike in IDA patients. Transferrin is a transport protein that is responsible for mediating the exchange of iron between tissues. Most of the iron transferred is derived from the iron stored in the macrophages and not from iron absorbed via the digestive tract. This affects transferrin levels in the blood in ACD because transferrin is a negative acute phase reactant. This means that during an infection or inflammation, the levels of transferrin in the blood decrease as the body tries to minimize the amount of iron accessible to pathogens and sequesters iron within macrophages. Also, most iron-bound transferrin is delivered to the bone marrow for erythropoiesis or tissues for storage, leaving the bloodstream. On the contrary in IDA, transferrin levels in the blood increase because the body is trying to accumulate iron by increasing the level of transferrin. These transferrin proteins aren’t bound to any iron, due to the deficiency, and circulate the bloodstream. 3. Describe the alternative method of assessing or identifying iron deficiency, which we have not discussed in class. The alternative method of  assessing or identifying iron deficiency mentioned in the paper was the use of flow cytometry to measure reticulocyte hemoglobin concentration (CHr). Reticulocytes are immature red blood cells that are only present for 1-2 days and are the most recently produced 1% of the erythrocytes. As such any sort of iron deficiency that affects proper erythropoiesis will be present upon analysis of reticulocyte hemoglobin concentration. Use of CHr as well as serum transferrin receptor levels to form diagnostic plots has been useful in identifying iron-restricted erythropoiesis (functional iron deficiency), regardless of whether or not an infection, an acute phase response, or ACD is concurrent. Thomas C, Thomas L. Biochemical markers and hematologic indices in the diagnosis of functional iron deficiency. Clin Chem. 2002;48:1066-1076. 4. How can iron supplementation work in ACD patients? How is it administered? Any drawbacks? In certain cases of ACD, iron supplementation can be therapeutic. Usually, since ACD is not a true iron deficiency, the anemia is resolved when the underlying condition of disease or inflammation is resolved. However, in some cases where the pathophysiological condition cannot be resolved, hematologists must instead target the issues that cause ACD, namely suppressed EPO production and increased iron sequestration as a result of excess hepcidin production. In the case of suppressed EPO production, iron supplements as well as rhEPO therapy can relieve the symptoms of anemia by inducing erythropoiesis. However, hematologists must also take into account that since excess hepcidin is being produced, the iron is unable to be absorbed via enterocytes, and must be administered intravenously. Because of the intravenous iron infusion, patients with ACD are at a high risk of being overloaded with iron and developing hemochromatosis. Drueke, T. B. â€Å"Intravenous Iron: How Much Is Too Much?† Journal of the American Society of Nephrology 16.10 (2005): 2833-835. 5. How have mouse models of ACD helped in the search for better management of ACD? Mouse models of ACD have helped in the search for better management of  ACD by providing two different methods of curbing excessive hepcidin production in those with ACD. Firstly, an ACD mouse was created by infection with Brucella. This mouse was then treated with a short-hairpin RNA sequence that would bind to the mRNA transcript products of the hepcidin gene. The mouse was found to have significantly less hepcidin concurrent with pre-inflammation levels, alleviating anemic symptoms. Secondly, the scientists were able to develop an anti-hepcidin antibody that would inhibit hepcidin production. They first created a knock-in mouse with a human hepcidin gene and then used the anti-hepcidin antibody as an effective treatment for anemia when used with ESA (similar to EPO in humans). Another mouse study was also able to inhibit a bone morphogenetic protein that is elevated (along with IL-6) in ACD patien ts and responsible for increase in hepcidin production making inhibiting of BMP a possible anemia treatment. Sasu BJ, Cooke KS, Arvedson TL et al. Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia. Blood. 2010;115:3616-3624. Steinbicker AU, Sachidanandan C, Vonner AJ, et al. Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation. Blood. 2011;117:4915-4923.

What Is Meant and How Can Government Attempt to Correct It?

What is meant by market failure and how can government attempt to correct it? Market failure occurs when there is no economic efficiency within a market. Whereas government intervention is put in use when a market may not always allocate scarce resources efficiently in a way that achieves the highest total social welfare. Monopolies are one of the main causes of market failure. Monopolies are firms whom have eliminated all, if not, most competitors within that market leaving them with most control within that market.The main reason why monopolies are negative within the economy is because they dictate pricing. After having eliminated most competitors, they then can start to charge whatever price they want for a product as the consumers can’t go elsewhere. As well as having increased the price of a product, they now have caused a limit in choice for the consumer. This is because the consumer can’t go for a cheaper product within that market as the monopoly has gotten rid of competition, thus leaving the consumer with high prices to pay at a limited choice.Another reason is because monopolies only have profit maximisation in mind. Profit maximisation is when a firm determines the price and output level that returns the greatest profit. Although the firm is maximising its profits, monopolies are allocatively inefficient. Monopolies tend to become complacent over time because pricing power, not gains from efficiency or innovation, drive profits. This means that due to the fact that they have stripped consumer surplus and experiencing vast profits, they are simply not allocating resources efficiently simply to do with its size.As a firm gets larger, it is more difficult for managers to be on top of every single thing that occurs within the company. Unnecessary waste could be caused meaning they aren’t allocating the finite resources efficiently, which isn’t beneficial in any economy. Due to a lack of innovation and efficiency, this also c auses allocative inefficiency as they now have to competition to compete on efficiency and new technology, which affects markets in negative manors.Walmart invested over one billion dollars to lose within the first year, by making prices of products incredibly cheaper than its competitors which drove them out of business, then increased prices in order to make back the losses and make huge profits whilst having removed all if not most competition. This is known as predatory pricing and is now very difficult to achieve because the governments noticed what had happened within that market and had to intervene in order to control market share within markets.Governments have now set a limit of 25% market share so that monopolistic behaviour doesn’t occur within a market, thus allowing other smaller business to compete or even simply enter for new businesses to enter. This is beneficial because firms will now have to compete on efficiency and innovation, so the push of new technolo gy through research and development creates a higher efficiency within a market as firms will now try to keep costs low instead of taking consumer surplus like monopolies. Inequality plays a large factor within causing market failure.This is because differences in wealth and income of different groups lead to a wider gap in living standards between households. Thus the division of rich and poor. Society itself may not find too much inequality acceptable. Those who are born into a rich background are more likely to be rich later in life, whereas some who are born into a poor background are a lot more likely to live a life of poverty. This is because those with richer backgrounds will have better education and up bringing thus increasing the chances of success later in life. In a free market, this isn’t the case.It is thought that all individuals have the opportunity to succeed. But, because of misallocation of resources in a free market economy this isn’t always the cas e. The way the government try to tackle this issue and making the gap smaller is normally by imposing a larger tax on the rich and create government programs which transfer this income to the poor. These are normally known as welfare benefits, unemployment benefits, public schools, NHS and some sort of support for economic development in poorer communities where unemployment and poverty is very high.Welfare benefits are very beneficial in spreading income to poorer people as they now have money to spend and inject back into the economy which also stimulates it but also increases their opportunities in life as they can afford things like gym memberships which make for a healthier and fitter labour force. However, nowadays, people have gotten lazy and inherited this life of living on benefits. This isn’t beneficial for the economy in the slightest as they are people who are capable of working and add to the labour force but choose not to as they believe they ive an easier life by given money for free by the tax payer. Public schools are put in place because it gives those with a poorer background a chance to be educated and more possibilities for the future. This increase in possibilities could lead to them from escaping a life of poverty, thus decrease gap between rich and poor. NHS is also one of the best health care systems devised, because it gives the chance for those who cannot afford to pay for doctors and hospital bills if anything were to happen, which leaves the economy with healthier people or simply people who can be treated when ill for free.However, this comes out of the tax payers pocket and seems very unfair for those who pay and never need to use NHS whereas there are some who don’t work and choose to, you can almost say ‘milk it’. Even though some choose to abuse it, NHS has had more positive outputs into the economy as it keeps the labour force treated of any injury or illness making for a more efficient labour force thus preventing market failure. A market may fail due to externalities.Externalities are benefits or costs which come from economic activity and affect someone other than those who are actually engaged in that economic activity and are not taken into account fully in the price we pay. Due to the fact that they aren’t taking into account of the price they are a form of market failure because the amount of the activity carried out, if left to the free market would not be an efficient use of resources.One of the main negative externalities which affects is pollution, for example, a city where manufacturing industries are based would be the cause of the pollution and poor environment as they pollute the air which we breathe, the rivers by dumping chemical waste and kill wild life. If a government weren’t to intervene then these externalities would become so severe that our atmosphere and environment could come to be so polluted that people become ill and die. These people are the labourers of that economy and if work force starts dying out this leads to a loss in production as people would need to be treated.Thus, eventually leading to market failure. One way the government can resolve this is by setting regulations for example, a ban. Another way is by determining whether it’s a negative or positive externality, and if it’s negative, impose a tax, if positive, a subsidy. A tax on negative externality would correct market failure as the cost for it is now being taken into account in the price. Overall, as we can see the government has devised many different forms of policies in order to prevent market failure.Monopolies, inequality and externalities are some of the main reason to explain why market failure occurs, however the government has overcome this. For example, with monopolies, they realise one business having most percentage of market share wasn’t beneficial to the market and consumers as there simply wouldn’t be any competition and an exploitation by that firm so they set a maximum of 25% market share so that there would be fair competition and competing with prices in order to offer the consumer the best possible price and product.

Simple sentences, period

Simple sentences, period Simple sentences, period Simple sentences, period By Michael A sentence should contain a complete thought. Once you finish your thought, you can finish your sentence, usually with a period. That makes your sentence more readable too. Yes, its legal in English to use conjunctions to put several thoughts into one sentence. But it takes a special kind of mind to follow the train of thought in a sentence that has two or three thoughts. Maybe some writers dont know when their thought ended, so they dont know when to put the period. They go on and on and make more and more statements and even change the subject, but they dont ever put the sentence to rest and keep on going and going. Technically speaking, to understand a complex sentence, the reader has to parse or diagram the sentence in his or her head. Okay, suppose Im reading a sentence in Rolling Stone. Was that sentence talking about actors, and what are the actors doing anyway, and what the subject of the sentence, and what is the subject doing, and does that word shot mean that somebody got shot or somebody took a shot, and does it refer to the policeman or the actor or the photographer? Pretty confusing, isnt it? So make your sentences simple. Put a period at the end of the thought and leave it there. Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Punctuation category, check our popular posts, or choose a related post below:Passed vs PastDo you "orient" yourself, or "orientate" yourself?40 Idioms with First

James Madison, 4th President of the United States

James Madison, 4th President of the United States James Madison (March 16, 1751–June 28, 1836) served as Americas 4th president, navigating the country through the War of 1812. Madison was known as the Father of the Constitution, for his role in its creation, and a man who served during a key time in the development of America.   Fast Facts: James Madison Known For: Americas 4th president and the Father of the ConstitutionBorn: March 16, 1751 in King George County, VirginiaParents:  James Madison, Sr. and Eleanor Rose Conway (Nelly), m. September 15, 1749Died: June 28, 1836 in Montpelier, VirginiaEducation: Robertsons School, College of New Jersey (which would later become Prrinceton University)Spouse: Dolley Payne Todd (m. September 15, 1794)Children: One stepson, John Payne Todd Early Life James Madison was born on March 16, 1751, the eldest child of James Madison, Sr., a plantation owner, and Eleanor Rose Conway (known as Nelly), the daughter of a wealthy planter. He was born at his mothers stepfathers plantation on the Rappahannock River in King George County, Virginia, but the family soon moved to James Madison Sr.s plantation in Virginia. Montpelier, as the plantation would be named in 1780, would be Madison Jr.s home for most of his life. Madison had six brothers and sisters: Francis (b. 1753), Ambrose (b. 1755), Nelly (b. 1760), William (b. 1762), Sarah (b. 1764), Elizabeth (b. 1768); the plantation also held more than 100 enslaved persons. The earliest education of James Madison, Jr. was at home, probably by his mother and grandmother, and at a school located on his fathers plantation. In 1758, he began attending the Robertson School, run by Scottish tutor Donald Robertson, where he studied English, Latin, Greek, French, and Italian, as well as history, arithmetic, algebra, geometry, and geography. Between 1767 and 1769, Madison studied under the rector Thomas Martin, who was hired by the Madison family for that purpose. Education Madison attended the College of New Jersey (which would become Princeton University in 1896) from 1769–1771. He was an excellent student and studied a range of subjects, including oratory, logic, Latin, geography, and philosophy. Perhaps more importantly, he made close friendships at New Jersey, included the American poet Philip Freneau, writer Hugh Henry Brackenridge, lawyer and politician Gunning Bedford Jr., and William Bradford, who would become the second attorney general under George Washington. But Madison grew ill in college, and stayed in Princeton after he graduated until April 1772, when he returned home. He was sickly most of his life, and modern scholars believe he likely suffered from epilepsy. Early Career Madison didnt have a vocation when he left school, but he soon became interested in politics, an interest perhaps stirred but at least fed by his continuing correspondence with William Bradford. The political situation in the country must have been exhilarating: his zeal for freedom from Britain was very strong. His first political appointment was as a delegate to the Virginia Convention (1776), and then he served in the Virginia House of Delegates three times (1776–1777, 1784–1786, 1799–1800). While in the Virginia house, he worked with George Mason to write Virginias constitution; he also met and established a lifelong friendship with Thomas Jefferson. Madison served on the Council of State in Virginia (1778–1779) and then became a member of the Continental Congress (1780–1783). Father of the Constitution Madison first called for a Constitutional Convention in 1786, and when it was convened in 1787 he wrote most of the U.S. Constitution, which outlined a strong federal government. Once the Convention ended, he, John Jay, and Alexander Hamilton together wrote the Federalist Papers, a collection of essays that were intended to sway public opinion to ratifying the new Constitution. Madison served as a U.S. Representative from 1789–1797. On September 15, 1794, Madison married  Dolley Payne Todd,  a widow and socialite who set the pattern for the behavior of White House first ladies for centuries to come. She was a well-liked hostess throughout Jeffersons and Madisons time in office, holding convivial parties with both sides of the Congress in attendance. She and Madison had no children, although John Payne Todd (1792–1852), Dolleys son from her first marriage, was raised by the couple; her son William had died in the 1793 yellow fever epidemic that killed her husband. In response to the Alien and Sedition Acts, in 1798 Madison drafted the Virginia Resolutions, a work that was hailed by anti-federalists. He was secretary of state under President Thomas Jefferson from 1801–1809. Embargo Act and the Presidency By 1807, Madison and Jefferson became alarmed at increasing reports on upheavals in Europe suggesting that Britain would soon go to war with Napoleons France. The two powers declared war and demanded that other nations needed to commit to a side. Since neither the Congress nor the administration were ready for all-out war, Jefferson called for an immediate embargo on all American shipping. That, said Madison, would protect American vessels from almost certain seizure, and deprive European nations of a needed trade that might force them to allow the U.S. to remain neutral. Passed on December 22, 1807, the Embargo Act would soon prove unpopular, an unpopularity that eventually led to U.S. involvement in the War of 1812. In the 1808 election, Jefferson supported Madisons nomination to run, and George Clinton was chosen to be his vice president. He ran against Charles Pinckney, who had opposed Jefferson in 1804. Pinckneys campaign centered around Madisons role with the Embargo Act; nevertheless, Madison won 122 of the 175 electoral votes. Negotiating Neutrality Early in 1808, Congress replaced the Embargo Act with the Non-Intercourse Act, which allowed the U.S. to trade with all nations except France and Great Britain because of the attacks on American shipping by those two nations. Madison offered to trade with either nation if it would stop harassing American ships. However, neither agreed. In 1810, Macons Bill No. 2 was passed, repealing the Non-Intercourse Act and replacing that with a promise that whichever nation would stop harassing American ships would be favored and the U.S. would stop trading with the other nation. France agreed to this and the British continued to stop American ships and impress sailors. By 1811, Madison easily won the renomination for the Democratic-Republicans, despite being opposed by DeWitt Clinton. The campaigns main issue was the War of 1812, and Clinton attempted to appeal to both those for and against the war. Madison won with 128 out of 146 votes. War of 1812: Mr. Madisons War When Madison started his second administration, the British were still forcibly attacking American ships, seizing their cargo, and impressing their sailors. Madison asked Congress to declare war: but support for it was far from unanimous. The war, sometimes called the Second War for Independence (because it resulted in the end of U.S. economic dependence on Britain), pitted a barely prepared U.S. against the well-trained force that was Great Britain. On June 18, 1812, Madison signed a declaration of war against Great Britain, after Congress, for the first time in American history, voted to declare war against another nation. Americas first battle was a disaster called the Surrender of Detroit: The British, led by Major General Isaac Brock, and Native American allies, led by the Shawnee leader Tecumseh, attacked the port city of Detroit on August 15–16, 1812. U.S. Brigadier General William Hull surrendered the town and fort, despite having a larger army. America fared better on the seas, and eventually retook Detroit. The British marched on Washington in 1814, and on August 23 they attacked and burned the White House. Dolley Madison famously stayed in the White House until she ensured that many national treasures were saved. The New England Federalists met at the Hartford Convention in late 1814 to discuss pulling out of the war, and there was even talk of secession at the convention. But, on December 24, 1814, the U.S. and Great Britain agreed to the Treaty of Ghent, which ended the fighting but resolved none of the pre-war issues. Retirement After his presidential term in office ended, Madison retired to his plantation in Virginia. However, he still stayed involved in political discourse. He represented his county at the Virginia Constitutional Convention (1829). He also spoke against nullification, the idea that states could rule federal laws unconstitutional. His Virginia Resolutions were often cited as a precedent for this but he believed in the strength of the union above all. He took a leadership role in the formation of the University of Virginia, especially after Thomas Jeffersons death in 1826. Madison was also a slave owner- Montpelier had 118 slaves at one point- who helped found the notorious American Colonization Society to help resettle freed blacks in what would become Liberia, Africa. Death Although Madison remained vigorous and active during his early retirement, beginning after his 80th birthday in 1829, he began to suffer from longer and longer spells of fever and rheumatism. Eventually he was confined to Montpelier, although he continued working when he could through the winter of 1835–1836. On June 27, 1836, he spent several hours writing a thank you note to George Tucker, who had dedicated his biography of Thomas Jefferson to him. He died the next day. Legacy James Madison was in power at an important time. Even though America did not end the War of 1812 as the ultimate victor, it did end with a stronger and independent economy. As the author of the Constitution, Madisons decisions made during his time as president were based on his interpretation of the document, and he was well-respected for that. In the end, Madison attempted to follow the Constitution and tried not to overstep the boundaries set before him as he interpreted them. Sources Broadwater, Jeff. James Madison: A Son of Virginia and a Founder of the Nation. Chapel Hill: University of North Carolina Press, 2012.Cheney, Lynne. James Madison: A Life Reconsidered. New York: Penguin Books, 2014.Feldman, Noah. The Three Lives of James Madison: Genius, Partisan, President. New York: Random House, 2017.Gutzman, Kevin R. C. James Madison and the Making of America. New York, St. Martins Press, 2012.Ketcham, Ralph. James Madison: A Biography. University of Virginia, 1990.

How the standards for ascertaining the truth differ between the new Essay

How the standards for ascertaining the truth differ between the new scientific views of the world and traditional medieval views - Essay Example How the standards for ascertaining the â€Å"truth† differ between the new scientific views of the world and traditional medieval views? Scientists often came up with different facts, conclusions and theories but when this happens, the process of science helps in resolving these differences. Science is therefore viewed as valuable as the scientific methods and the scientific community can resolve any differences and come to a generally accepted conclusion because the overarching commitment of science is to â€Å"the truth† about the natural world. The medieval view of the world is based on old traditions and religious doctrines. Traditions defined people and their culture while religious doctrines defined the way people lived in the society. Christians sought to integrate traditions with religion and the result was one God, one church and one truth. These doctrines and traditions explained the world (Barret 12-13). All scientists are involved in the same enterprise of trying to explain how the world works. They believe in the scientific process of observation, experimentation and the development and evaluation of explanatory theories. The new scientific view seeks the absolute truth through scientific processes of observation and experimentation. It believes in the existence of fixed and unalterable facts and these can only be reached after detailed scientific investigation. The medieval standards adapted the truth to match their predetermined views. To them truth was based on tradition and religious views that defined what was true.